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KMID : 1144620190320020111
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Journal of Trauma and Injury
2019 Volume.32 No. 2 p.111 ~ p.114
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Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature
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Depa Jayaramakrishna
Coritsidis George
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Abstract
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Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD.
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KEYWORD
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Minimal change disease, Skin injury, Recurrence, Nephrology, End-stage renal disease
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